Ph.D. student, Kate Castellano, from the R. O'Neill Laboratory
Multiplexed fluorescent in situ hybridization...TS12-Tail-Stock (submitted by the Nelson Laboratory)
Barbara Mellone, Associate Professor of Molecular and Cell Biology, works in her lab at the Institute of Systems Genomics in the Engineering & Science Building
Prof. Rachel O'Neill presenting at the Institute for Systems Genomics 5 year anniversary celebration
Professor Leighton Core and Ph.D. student Luke Wojenski discussing research in the Core Lab
L>R: Savannah Klein, Kate Castellano, Syed Farhan Ahmad, and Melinda Wei work on a group project at the Institue for Systems Genomics in the Engineering & Science Building (Bri Diaz/UConn Photo)
Bryce Santinello, Mellone lab imaging Drosophila chromosomes on a Deltavision microscope
The Genetics and Genomics Program comprises faculty encompassing an array of multidisciplinary fields in genetics, genomics, and bioinformatics, and is partnered with the newly established Institute for Systems Genomics. Students in the Molecular and Cell Biology graduate program may pursue a Masters or Ph.D. degree in this area of concentration. Students interested in careers in the biotechnology and pharmaceutical industries may also pursue an MS degree in Applied Genomics in the Professional Science Master’s (PSM) program (Contact psm@uconn.edu for more information).
Areas of research focus include chromosome structure and function, comparative genomics and genome evolution, developmental genetics, molecular evolution, control of transcription, modulation of noncoding RNAs, human genomics, animal models for genome biology, centromere biology, and epigenetics.
CONTACT
Barbara Mellone, Program Head
phone: (860)486-9223
email: barbara.mellone@uconn.edu
G & G News
- Dr. Rachel O’Neill Inducted Into the Connecticut Academy of Science and EngineeringRachel J. O’Neill, Institute for Systems Genomics, Molecular & Cellular Biology, Genetics and Genome Sciences, College of Liberal Arts and Sciences to be inducted into the Connecticut Academy of Science and Engineering (CASE) for 2020. According to CASE, election to the Academy is based on the applicant’s scientific and engineering distinction, achieved through significant contributions […]Posted on March 24, 2020
- Fake Centromeres Make-and Break-a ChromosomeThe Mellone Lab was featured in UConn Today – UConn cell biologist Barbara Mellone, her student Jason Palladino, and colleagues report in the cover article of the 10 February issue of Developmental Cell that they were able to make fake centromeres that fooled cells into rearranging their chromosomes. Fluorescence images of mitotic cells with de novo […]Posted on February 26, 2020
- Professor Barbara Mellone Awarded NIH awardMCB Associate Professor Barbara Mellone received a $2.6million R35-MIRA grant from the National Institute of Health to fund her research on an elusive yet vital chromosomal structure that all plant and animal share: the centromere. This five-year grant will support research efforts to determine the contribution of DNA repeats and centromere chromatin to the formation […]Posted on September 5, 2019